Forschungsgruppe MR-Physik, Fraunhofer MEVIS


The MR physics group at Fraunhofer MEVIS was established in November 2009. It develops new measurement approaches to improve and speed up MR imaging. The range of applications is rather broad, but all methods have a strong focus on good applicability.

Main research topics are:         

  • Physiological imaging Perfusion imaging without contrast agents using arterial spin labeling (ASL).
    • Velocity-selective ASL for an improved blood labeling, for example in breast perfusion
    • 3D GRASE PROPELLER for motion corrected ASL, particularly interesting for perfusion in organs other than brain, like in kidney
    • Improved reproducibility and robustness in ASL-CBF quantification.
  • Prospective Motion Correction in MRI A novel 2D-EPI-navigated prospective motion correction technique has been developed to correct for in-plane and through-plane motion that establishes a flexible steady-state during the measurement. Results show a substantial reduction of motion parameters and an increase in overall image quality in comparison to a no-motion scan. The technique can be adapted to limit the effect on the overall scan time or the contrast-to-noise ratio. This technique is currently developed to improve fMRI experiments.
  • Accelerated MRI:
    • Simultaneous Multi-Contrast Imaging: The technique reduces patient examination times and facilitates accurate image registration between contrasts. The proposed combination of contrasts has clinical significance in acute stroke, providing a registered data set for assessing the infarct and possibility of associated hemorrhage.
    • Accelerated Magnetic Resonance Spectroscopic Imaging Using Readout Segmentation (ASPIRES): ASPIRES is a novel method for accelerated, high-resolution, large-bandwidth echo-planar spectroscopic imaging.  It is very promising to enhance the diagnostic performance of MR spectroscopic imaging in clinical routine and improve the study of metabolites at high field strengths.
  • Ultra short Echo Time MRI Implementation of an automatic calibration measurement for UTE imaging, that is of clinical interest for imaging of very short T2* tissues, for the evaluation of water content in the cortical bone and for X-nuclei imaging.
  • Simultaneous MR- and Ultrasound-Imaging A lot of effort has been spent over the last years to make ultrasound imaging MR-compatible and provide a system, which allows for simultaneous acquisition of ultrasound and MR images. At the moment the KOMBUS project, funded by the BMBF, is devoted to the clinical validation of an innovative breast biopsy procedure that is driven by real-time ultrasound imaging fused with previously acquired MRI.



Am Falturm 1
28359 Bremen
Tel.: 49-421-218-59112
Fax: 49-421-218-59277

Prof. Dr. Matthias Guenther
Tel.: 49-421-218 59112